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Glossary infobadge

This glossary contains a number of definitions  from the following publication:
J. M. Cock; Tessmar-Raible, K.; Boyen, C.; Viard, F. (Eds.), Introduction to Marine Genomics, vol. 1, 1st ed., Advances in Marine Genomics Vol. (Springer, 2010). Available from: http://www.springer.com/life+sciences/ecology/book/978-90-481-8616-7?cm_mmc=Google-_-Book%20Search-_-Springer-_-0

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Term Definition
Sporophyte

A spore-producing plant.

Spot/feature

A small area on the surface of a microarray containing a defined probe. Features can be produced using a spotter or by direct synthesis of oligonucleotides on the substrate.

SSR

Simple Sequence Repeat; also known as microsatellite.

SteN

Statistical electronic Northern blot.

SVM

Support Vector Machine, high performance machine learning technique that has been used to improve classification accuracy in biological applications such as gene prediction, detection of protein family members, RNA and DNA binding proteins and the functional classification of gene expression data. SVMs can solve non-linear classification problems by learning an optimally separating hyperplane in a higher-dimensional feature space. By use of non-linear kernel functions such as a Gaussian kernel, complex and non-linear decision functions can be realised.

Synteny

Evolutionary preservation of the order of genes in a genomic region that indicates that this order also reflects the arrangement of genes in the last common ancestor of two compared species. Subdivided into macro-synteny (conserved aspects on the chromosomal level) and micro-synteny (local, gene-by-gene synteny).

Target

In a microarray experiment, the target is labelled population of molecules corresponding to the RNA or DNA extracted from mixtures of cells, tissues, cell cultures or other samples. This labelled population of molecules is often referred to erroneously as the probe.

TC

Tentative Consensus Sequence. EST sequences can be clustered together using assembly programs to form TCs.

Tertiary endosymbiosis

An event in which a eukaryotic cell enslaves another eukaryotic cell that possesses a plastid derived from a secondary endosymbiosis (see secondary endosymbiosis). This has occurred several times in the dinoflagellates, and the captured plastid is thought to have replaced a pre-existing Secondary plastid (see also endosymbiosis).

TETRA

A tool that can be used to calculate, how well tetranucleotide usage patterns in DNA sequences correlate. Such correlations can provide valuable hints about the relatedness of DNA sequences.

TGICL

TIGR Gene Index Clustering tools.

Third Party annotation (TPA) sequence da

 

A database designed to capture experimental or inferential results that support submitter-provided annotation for sequence data that the submitter did not directly determine but can be derived from DDBJ/EMBL/GenBank primary data.

Transcriptome

The full complement of transcripts in a given species.

Transcriptomics

High-throughput analysis of the rnRNA transcripts present in a cell type, a tissue or an organism.

UTR

Untranslated region of a transcript. The complementary regions to the ORF (see ORF).

Web services

Provide a standardized method to access information or perform computations over a network via the exchange of XML based messages Western blot.

Western blot

A method for analysing proteins involving separation on by SDS-PAGE and detection of specific proteins using antibodies.

XML

Extended Markup Language, a specification to create a common representation of different types of data.

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